What does high renin indicate?
What does high renin indicate? A high renin value can mean that kidney disease, blockage of an artery leading to a kidney, Addison's disease, cirrhosis, excessive bleeding (hemorrhage), or a hypertensive emergency is present. What causes increased renin production? Increased renin release from the juxtaglomerular cells is caused by several conditions: reduction in renal blood flow from heart failure, blood loss, hypotension or ischemia of the kidneys, sodium diuresis (excessive sodium loss in urine), and beta-adrenergic stimulation. What happens when renin increases? An excessive increase in renin could potentially limit the effectiveness of renin inhibition, either because Ang II generation...