What is the difference between MEN2A and MEN2B?
What is the difference between MEN2A and MEN2B? Differences in presentation MEN2A is additionally characterized by the presence of parathyroid hyperplasia. MEN2B is additionally characterized by the presence of mucocutaneous neuroma, gastrointestinal symptoms (e.g. constipation and flatulence), and muscular hypotonia. MEN2B can present with a Marfanoid habitus. How common is MEN2A? How common is MEN2A? MEN2A is a rare condition occurring in approximately 1 in 40,000 people. What is MTC or MEN2? Multiple endocrine neoplasias type 2 (MEN2) is an inherited disorder characterized by the development of medullary thyroid cancer (MTC), parathyroid tumors, and pheochromocytoma. MEN2 results from germline mutations...