What does CDX2 gene do?
What does CDX2 gene do? Cdx2 regulates E-cadherin function indirectly by disrupting receptor tyrosine kinase activity and enhancing E-cadherin trafficking to the cell membrane compartment. Data indicate that CDX2 directly regulates MDR1 gene expression through binding to elements in the promoter region. What are CDX2 cells? The CDX2 protein is a homeobox transcription factor expressed in the nuclei of intestinal epithelial cells, playing an essential role in the development and function of the digestive system. CDX2 part of the ParaHox gene cluster, a group of three highly conserved developmental genes present in most vertebrate species. Is CDX2 a transcription factor?...