Does Russell-Silver syndrome affect intelligence?

The majority of individuals with RSS are of normal intelligence, but motor and/or speech delay is common. RSS is genetically heterogeneous, meaning that different genetic abnormalities are known to cause the disorder. Abnormalities involving chromosomes 7 or 11 have been found in up to 60% of RSS patients.

What is Russell Silvers Syndrome?

Russell-Silver syndrome (RSS), sometimes called Silver-Russell syndrome (SRS), is a congenital condition. It is characterized by stunted growth and limb or facial asymmetry. Symptoms range over a broad clinical spectrum from severe to so mild that they go undetected. The disorder is caused by very rare genetic defects.

Is Beckwith Wiedemann syndrome maternal imprinting?

Beckwith–Wiedemann syndrome (BWS) is an imprinting disorder characterized by overgrowth, tumor predisposition, and congenital malformation(s). Approximately 85% of reported BWS cases are sporadic, with the remaining 15% considered to be familial.

What syndrome is related to BWS but have reverse symptoms?

Silver-Russell syndrome (SRS) and Beckwith-Wiedemann syndrome (BWS) are 2 clinically opposite growth-affecting disorders belonging to the group of congenital imprinting disorders. The expression of both syndromes usually depends on the parental origin of the chromosome in which the imprinted genes reside.

Can Russell-Silver syndrome have a baby?

Russell-Silver syndrome is a growth disorder characterized by slow growth before and after birth. Babies with this condition have a low birth weight and often fail to grow and gain weight at the expected rate (failure to thrive).

How do you know if your child has Russell-Silver syndrome?

Russell-Silver syndrome (RSS) is a rare condition associated with poor growth both before and after birth. Signs and symptoms vary and may include low birth weight, short stature , characteristic facial features, large head in relation to body size, body asymmetry, and feeding difficulties.

Can people with Russell-Silver syndrome have children?

An adult female with typical features of Silver-Russell dwarfism gave birth to a viable infant. Despite the abnormalities in sexual development that may be associated with the Silver-Russell syndrome, fertility is not necessarily impaired, at least in females.

What is Beckwith?

Beckwith-Wiedemann syndrome is a condition that affects many parts of the body. It is classified as an overgrowth syndrome, which means that affected infants are larger than normal (macrosomia), and some may be taller than their peers during childhood.

Is Russell-Silver syndrome a genetic disorder?

Russell-Silver syndrome (RSS) is a genetic disorder that usually results from the abnormal regulation of certain genes that control growth.