What is Rocephin ceftriaxone used for?

Rocephin (ceftriaxone sodium) for Injection is a cephalosporin antibiotic used to treat many kinds of bacterial infections, including severe or life-threatening forms such as meningitis.

What should you assess before giving Rocephin?

Examination and Evaluation

Watch for seizures; notify physician immediately if patient develops or increases seizure activity.
Monitor signs of pseudomembranous colitis, including diarrhea, abdominal pain, fever, pus or mucus in stools, and other severe or prolonged GI problems (nausea, vomiting, heartburn).

What are the indications of ceftriaxone?

Indications for: Ceftriaxone Susceptible bacterial infections of the lower respiratory tract, skin and skin structure, bone and joint, acute otitis media, UTIs, septicemia, pelvic inflammatory disease (PID), intraabdominal infections, meningitis, uncomplicated gonorrhea.

What is the mechanism of action of ceftriaxone?

Ceftriaxone works by inhibiting the mucopeptide synthesis in the bacterial cell wall. The beta-lactam moiety of ceftriaxone binds to carboxypeptidases, endopeptidases, and transpeptidases in the bacterial cytoplasmic membrane. These enzymes are involved in cell-wall synthesis and cell division.

What are the contraindications of ceftriaxone?

Who should not take CEFTRIAXONE?

diarrhea from an infection with Clostridium difficile bacteria.
a type of blood disorder where the red blood cells burst called hemolytic anemia.
liver problems.
disease of the gallbladder.
severe renal impairment.
yellowing of the skin in a newborn child.

What type of drug is ceftriaxone?

Ceftriaxone belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections. This medicine is available only with your doctor’s prescription.

How do you do a sensitivity test for ceftriaxone?

Sensitivity test should be performed by initial administration of 1 ml of ceftriaxone as a test dose, and only after that the rest of the antibiotic is to be given as a slow intravenous infusion ([Table – 2]).

What is the frequency of ceftriaxone?

Hide table of contents

Ceftriaxone dosage*	Treatment frequency	Indications
20-50 mg/kg	Once daily	Infections of bones and joints
Management of neutropenic patients with fever that is suspected to be due to a bacterial infection
50 mg/kg	Once daily	Bacterial meningitis
Bacterial endocarditis

What is the contraindication of ceftriaxone?

Hypersensitivity. Rocephin is contraindicated in patients with known hypersensitivity to ceftriaxone, any of its excipients or to any other cephalosporin.