Does brittle bone disease affect the brain?
Does brittle bone disease affect the brain?
Osteogenesis imperfecta (OI) is a rare genetic disorder characterized by disruption of normal collagen formation resulting in varying degrees of skeletal vulnerability, ligamentous laxity, and scleral discoloration. Children with OI may suffer from complex neurosurgical problems affecting the brain and spine.
Does brittle bone disease get worse over time?
In type 3 OI, your child’s body produces enough collagen but it’s poor quality. Your child’s bones can even begin to break before birth. Bone deformities are common and may get worse as your child gets older.
How long does someone with brittle bone disease live?
Life expectancy for males with OI was 9.5 years shorter than that for the general population (72.4 years vs 81.9 years), and for females, was 7.1 years shorter than that for the general population (77.4 years vs 84.5 years).
What happens in the body to cause osteogenesis imperfecta?
OI is caused by defects in or related to a protein called type 1 collagen (pronounced KOL-uh-juhn). Collagen is an essential building block of the body. The body uses type 1 collagen to make bones strong and to build tendons, ligaments, teeth, and the whites of the eyes.
Is Brittle bones a disability?
Osteoporosis itself doesn’t cause any pain or symptoms, so doesn’t automatically qualify as a disability. If you’re experiencing persistent pain, a change in posture or problems getting around because of broken bones, you may be entitled to benefits.
What is the emotional effect of osteoporosis?
Osteoporosis can also cause both social consequences and psychological difficulties for patients with this disease: loss of social roles, failure in social reciprocity, social isolation, loneliness, depression, anxiety, reduced self-worth, and hopelessness.
How does brittle bone disease affect everyday life?
Severe forms of the disease can affect the shape of the rib cage and spine, which can lead to life-threatening breathing problems. Some people may need to be on oxygen. But in many other cases, people with this condition live a healthy, productive life with monitoring on a regular basis and the right treatment.
Is brittle bone disease painful?
Does brittle bone disease cause pain? The defective brittle bones themselves are not painful, but chronic pain may develop in some people with osteogenesis imperfecta due to repeated fractures and skeletal changes. Pain may also result from acute injuries such as fractures.
How is the family of a person with osteogenesis imperfecta affected?
It also affected family dynamics. Parents said they usually gave the child with OI increased attention, which meant less time and energy for siblings and their spouse. Consequently sometimes siblings felt abandoned and relationships between parents suffered.
How does osteoporosis affect a person’s life?
Many individuals who suffer fractures as a result of osteoporosis suffer significant pain, height loss, and may lose the ability to dress themselves, stand up, and walk. These patients are also at risk of acute complications such as pressure sores, pneumonia, and urinary tract infections.
Can osteoporosis make you tired?
Following a fracture, bones tend to heal within six to eight weeks but pain and other physical problems, such as pain and tiredness or fatigue, may continue.
What is the prognosis for brittle bone disease?
The long-term outlook varies depending on the type of brittle bone disease. Outlooks for the four main types of brittle bone disease are: If your child has type 1 OI, they can live a normal life with relatively few problems. Type 2 OI is often fatal. A child with type 2 OI may die in the womb or shortly after birth from respiratory problems.
What causes bones in the human body to become brittle?
Brittle bone disease is passed down through families, or inherited. It’s caused by a defect in a gene that is supposed to make a substance called collagen. Collagen is a protein in your body that forms and strengthens bones. If you don’t have enough of it, your bones become very weak and will break easily.
What is the life expectancy of someone with Oi?
The lifespan ranges from very brief to average. The life expectancy of OI sufferers is quite similar to individuals with average health. Usually, individuals with moderate or mild symptoms do not have any impact on their lifespan. However, those suffering from acute symptoms may have a short lifespan.
What is the treatment for brittle bone disease?
physical and occupational therapy to increase your child’s mobility and muscle strength