What are the applications of mass spectrometry?

Specific applications of mass spectrometry include drug testing and discovery, food contamination detection, pesticide residue analysis, isotope ratio determination, protein identification, and carbon dating.

What is the basic principle of mass spectrometry and its application?

“The basic principle of mass spectrometry (MS) is to generate ions from either inorganic or organic compounds by any suitable method, to separate these ions by their mass-to-charge ratio (m/z) and to detect them qualitatively and quantitatively by their respective m/z and abundance.

What is the importance of mass spectrophotometer?

Mass spectrometry has gradually become an important tool in food quality and safety evaluation, playing an important role in the analysis of food quality components, pesticide residues, environmental persistent pollutants, and others in recent years, thus ensuring the quality, reliability, and safety of food.

What is atomic mass spectroscopy?

In the analytical technique of mass spectrometry, atoms or molecules are ionized using a high-energy electron beam and then separated based on their mass-to-charge ratios (m/z). This data can be used to calculate the exact masses of the atoms or molecules in the sample.

How does the mass spectrometer work?

A mass spectrometer can measure the mass of a molecule only after it converts the molecule to a gas-phase ion. To do so, it imparts an electrical charge to molecules and converts the resultant flux of electrically charged ions into a proportional electrical current that a data system then reads.

What are the three essential components of a mass spectrometer?

Every mass spectrometer consists of three basic components; the ion source, the analyzer, and the detector system. The ion source is used to generate gaseous ions from the sample, which are required to perform the measurement.

What is atomic spectroscopy used for?

Atomic spectroscopy is primarily used for the determination of trace metals in many types of samples composed of organic or inorganic matrices. The techniques used for this purpose are atomic emission spectroscopy and atomic absorption spectroscopy.

How does the mass spectrometer works?

Why is mass spectrometry better than other techniques?

Mass spectrometry is sensible and precise Coupled to liquid chromatography (LC), LC-MS can deliver highly precise quantification. Also, when performed by experts, it is highly reproducible and accurate over several orders of magnitude (of course, this is molecule-dependant!).

Is mass spectrometry quantitative or qualitative?

Mass Spectrometry is not inherently quantitative due to the different properties of our sample components. Therefore, the technique is qualitative unless you have calibration curves.

How is mass spectrometry used in drug testing?

Mass spectrometry (MS) is the most discriminatory of the drug testing techniques. Mass spectrometry measures the precise molecular mass of ions as determined by their mass to charge ratio (m/z) and is the current gold standard in forensic drug analysis [17].