What are the examples of Nitroimidazole?

Names of nitroimidazoles include:

Flagyl.
Flagyl ER.
Flagyl IV RTU.
Metronidazole.
Secnidazole.
Solosec.
Tindamax.
Tinidazole.

What is a nitroimidazole antibiotic?

Nitroimidazole antibiotics are used to treat parasitic infections, amoebiasis, bacterial vaginosis, gastrointestinal infections, skin infections, meningitis, lower respiratory infections, bacterial infections, diarrhea, and rosacea. They work by killing the bacteria causing the infection.

What is refractory giardiasis?

Giardia is a cause of disease both in diarrheal and nondiarrheal cases. The prevalence of treatment refractory giardiasis is increasing. Recent studies reveal 5-nitroimidazole refractory infection occurs in up to 50% of cases. Mechanisms of drug resistance are not known.

What is the mechanism of action of metronidazole?

Mechanism of Action Metronidazole diffuses into the organism, inhibits protein synthesis by interacting with DNA and causing a loss of helical DNA structure and strand breakage. Therefore, it causes cell death in susceptible organisms.

Is nitroimidazole and metronidazole same?

Metronidazole belongs to the nitroimidazole class of antibiotics and is active against protozoa in addition to anaerobic bacteria. It is bactericidal to anaerobic organisms through formation of free radicals that inhibit DNA synthesis and cause DNA degradation.

What are the derivatives of nitroimidazole?

Drugs of the 5-nitro variety include metronidazole, tinidazole, nimorazole, dimetridazole, pretomanid, ornidazole, megazol, and azanidazole. Drugs based on 2-nitromidazoles include benznidazole. Nitroimidazole antibiotics have been used to combat anaerobic bacterial and parasitic infections.

What are the derivatives of Nitroimidazole?

How long does it take to recover from Giardia after treatment?

Most people with giardiasis fully recover within two months after having mild to moderate digestive symptoms. Some people continue to have gastrointestinal symptoms (such as lactose intolerance or irritable bowel syndrome) long after the infection is gone.

What is the best medicine for Giardia?

Metronidazole (Flagyl). Metronidazole is the most commonly used antibiotic for giardia infection. Side effects may include nausea and a metallic taste in the mouth.