What class of drugs is letrozole?

Letrozole is in a class of medications called nonsteroidal aromatase inhibitors. It works by decreasing the amount of estrogen produced by the body. This can slow or stop the growth of some types of breast cancer cells that need estrogen to grow.

Why was letrozole banned?

That study also found no significant difference in the rate of overall abnormalities, but found that congenital cardiac anomalies was significantly higher in the clomiphene group compared to the letrozole group. Despite this, India banned the usage of letrozole in 2011, citing potential risks to infants.

Is letrozole considered to be a chemotherapy drug?

Letrozole is not chemotherapy, it is a type of hormone therapy that is used to treat people with breast cancer that is hormone receptor-positive.

Is letrozole an immunosuppressant drug?

siponimod and letrozole both increase immunosuppressive effects; risk of infection. Use Caution/Monitor. Caution if coadministered because of additive immunosuppressive effects during such therapy and in the weeks following administration.

What are the long term side effects of letrozole?

Side effects that are more likely to take a few months to develop and persist long term include:

blood changes, such as decreases in white blood cell counts or platelets.
edema (swelling that usually affects your hands, feet, legs, or arms)
hair loss.
high cholesterol.

Does letrozole cause anxiety?

Although they’re not common side effects, in some cases, Femara can cause anxiety or depression.

Is anxiety a side effect of letrozole?

Tell your doctor right away if you have any serious side effects, including: bone fractures, mental/mood changes (such as depression, anxiety), swelling of arms/legs, blurred vision, persistent nausea/vomiting, unusual tiredness, dark urine, yellowing eyes/skin..

Does letrozole make you emotional?

On letrozole, the same patient developed “an acute irritable activated mood” followed by a prolonged period of depression after its discontinuation (Goodwin, 2006). Side effects of aromatase inhibitors include changes in mood, mental state, cognition, and behavior.