What intensity statin is livalo?
What intensity statin is livalo?
Table 1Statin Dosing and ACC/AHA Classification of Intensity
| Statin | Dosage | |
|---|---|---|
| Low-intensity (LDL-C reduction <30%) | Moderate-intensity (LDL-C reduction 30% to <50%) | |
| Fluvastatin | 20 to 40 mg | 40 mg 2×/day; XL 80 mg |
| Lovastatin | 20 mg | 40 mg |
| Pitavastatin | 1 mg | 2 to 4 mg |
Can pitavastatin be replaced by atorvastatin for this patient?
Conclusion: Pitavastatin is equivalent to atorvastatin in reducing LDL-C in primary hypercholesterolemia or combined dyslipidemia, in both the lower-dose (pitavastatin 2 mg vs atorvastatin 10 mg) and higher-dose (pitavastatin 4 mg vs atorvastatin 20 mg) comparisons.
Is pitavastatin high-intensity?
In contrast, “high-intensity or high-dose statins” in Japan, such as pravastatin 40-80 mg, atorvastatin 10-20 mg, rosuvastatin 5-10 mg, and pitavastatin 2-4 mg are listed within the “moderate-intensity” statin group in the ACC/AHA guideline [5].
Is livalo a strong statin?
Livalo reduces levels of total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C) and triglycerides (TG) to a similar level as the most potent statins, simvastatin and atorvastatin.
Is Livalo better than atorvastatin?
Bottom line: Livalo is very effective at increasing high-density lipoprotein-cholesterol (HDL-C) levels. Livalo is very effective at decreasing levels of total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C) and triglycerides (TG). Livalo has less drug-drug interaction than atorvastatin and simvastatin.
How effective is Livalo?
Like other statins, Livalo affects all aspects of your cholesterol profile: It lowers LDL and triglycerides and raises HDL. Pivotal studies examining the effect of Livalo on lipid levels has shown that: LDL cholesterol is lowered by up to 44%. Total cholesterol levels are lowered by about 32%.
Which statin is the strongest?
Rosuvastatin and atorvastatin are the strongest statins because they have long half-lives. – Atorvastatin, simvastatin, and lovastatin are metabolized by the P450 cytochrome 3A4, which is inhibited by many other drugs and may thereby increase the risk of myopathy.
What strength statin should I take?
Dosage. The usual dose for adults is between 10mg and 80mg a day. In children, the usual dose is 10mg to 20mg once a day. Your doctor will use your child’s age to work out the amount of atorvastatin that’s right for them.
Who qualifies for high-intensity statin?
Four groups of patients are recommended for intense statin treatment: Adults with clinical ASCVD, which encompasses coronary artery disease, peripheral artery disease, transient ischemic attack or stroke. Adults age 40 to 75 with diabetes. Adults of any age with LDL above 190.
Who should not take Livalo?
You should not use Livalo if you are allergic to pitavastatin, or if you have:
- liver disease (including significantly abnormal liver enzyme tests);
- if you are pregnant or breastfeeding; or.
- if you are taking cyclosporine.