What is fosaprepitant used for?
What is fosaprepitant used for?
Fosaprepitant injection is used with other medicines to prevent nausea and vomiting caused by cancer treatment (chemotherapy). It acts in the brain to prevent nausea.
What is the difference between fosaprepitant and aprepitant?
Fosaprepitant is a prodrug of aprepitant, and it is converted to aprepitant within 30 minutes when administered intravenously.
How much does fosaprepitant cost?
Fosaprepitant is a cost-effective antiemetic medication when compared to the three-day oral aprepitant antiemetic regimen, which costs about $705 (Lexicomp, 2016a). The single dose of fosaprepitant costs about $320 (Lexicomp, 2016b).
What is another name for fosaprepitant?
Fosaprepitant
| Clinical data | |
|---|---|
| Trade names | Emend, Ivemend |
| AHFS/Drugs.com | Professional Drug Facts |
| MedlinePlus | a604003 |
| License data | EU EMA: by INN US DailyMed: Fosaprepitant US FDA: Fosaprepitant |
Is fosaprepitant chemotherapy?
Fosaprepitant is used with other medications to help prevent nausea and vomiting caused by cancer drug treatment (chemotherapy). Fosaprepitant works by blocking one of the body’s natural substances (substance P/neurokinin 1) that causes vomiting.
Is fosaprepitant a prodrug?
Rationale for fosaprepitant It is an intravenous prodrug of the orally administered anti-emetic aprepitant, the first clinically available NK1 receptor antagonist to be indicated for CINV.
How much does Emend IV cost?
The cost for Emend for Injection intravenous powder for injection 150 mg is around $359 for a supply of 1 powder for injection, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
How do you give fosaprepitant?
Administer EMEND for injection on Day 1 as an intravenous infusion over 20 to 30 minutes (adults), 30 minutes (12 years to 17 years) or 60 minutes (6 months to less than 12 years) completing the infusion approximately 30 minutes prior to chemotherapy. In pediatrics, administer EMEND through a central venous catheter.
Can you take omeprazole during chemo?
When applied as an adjuvant drug in cancer treatment for relieving common side effects of chemotherapy, omeprazole has a synergetic effect in improving CRT efficacy and decreasing rectal cancer recurrence.