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What is Hypochloremic metabolic alkalosis?

What is Hypochloremic metabolic alkalosis?

Hypochloremic alkalosis results from either low chloride intake or excessive chloride wasting. Whereas low chloride intake is very uncommon, excessive chloride wasting often occurs in hospitalized children, usually as a result of diuretic therapy or nasogastric tube suctioning.

What does metabolic alkalosis mean?

Metabolic alkalosis is defined as elevation of the body’s pH above 7.45. Metabolic alkalosis involves a primary increase in serum bicarbonate (HCO3-) concentration, due to a loss of H+ from the body or a gain in HCO3-.

What is chloride-responsive metabolic alkalosis?

Chloride-responsive alkalosis results from loss of hydrogen ions, usually by vomiting or dehydration. Chloride-resistant alkalosis results when your body retains too many bicarbonate (alkaline) ions, or when there’s a shift of hydrogen ions from your blood to your cells.

What causes Hypochloremia?

Causes of Hypochloremia: Loss of body fluids from prolonged vomiting, diarrhea, sweating or high fevers. Drugs such as: bicarbonate, corticosteroids, diuretics, and laxatives.

How does metabolic alkalosis cause hyponatremia?

Metabolic alkalosis is an elevated arterial pH of above 7.45, and is the consequence of disorders that cause either a loss of hydrogen ions from the body or an increase in plasma bicarbonate from a normal value of 24 mEq/L. Causes include gastric secretion loss (e.g., vomiting) and mineralocorticoid excess.

What is Hyperchloremic alkalosis?

Nevertheless, hyperchloremia can occur when water losses exceed sodium and chloride losses, when the capacity to handle excessive chloride is overwhelmed, or when the serum bicarbonate is low with a concomitant rise in chloride as occurs with a normal anion gap metabolic acidosis or respiratory alkalosis.

How does hypochloremia cause metabolic alkalosis?

Hypochloremia can contribute to the maintenance of metabolic alkalosis by increasing the reabsorption of and reducing the secretion of bicarbonate in the distal tubule. Increased distal reabsorption of bicarbonate. Click to see full answer. Likewise, people ask, why does low chloride cause metabolic alkalosis?

How is hypochloremia diagnosed in diabetic ketoacidosis?

A Chem 7 test should be performed, then urine chloride should be analyzed to determine whether chloride‚Äźresponsive alkalosis is present. The diagnosis of hypochloremia is made based on the patient’s history of diuretic therapy, vomiting, or nasogastric suctioning along with the assessment of chloride values in the presence of metabolic alkalosis.

What are the signs and symptoms of hypochloremia?

There are no specific signs or symptoms of hypochloremia. A Chem 7 test should be performed, then urine chloride should be analyzed to determine whether chloride‚Äźresponsive alkalosis is present.

What causes hypochloremic alkalosis in pediatric ICU?

Hypochloremic alkalosis due to loss of gastric acid via nasogastric tube suctioning is also common in pediatric ICUs.