What is ledipasvir used to treat?

Ledipasvir and sofosbuvir combination is used with or without ribavirin to treat chronic hepatitis C infection in adults and children 3 years of age and older (including liver transplant patients, with or without cirrhosis). This product is available in the following dosage forms: Packet. Tablet.

What is Ledipasvir Sofosbuvir used for?

The combination of ledipasvir and sofosbuvir is used alone or in combination with ribavirin (Copegus, Rebetol, Ribasphere, others) to treat certain types of chronic hepatitis C (an ongoing viral infection that damages the liver) in adults and children 3 years of age and older.

What is the mechanism of action of ledipasvir?

Ledipasvir is an NS5A inhibitor that is effective against genotypes 1a, 1b, 4a, and 5a and (with lower activity) against genotypes 2a and 3a. Its exact mechanism of action is unknown, but one suggested mechanism is its inhibition of hyperphosphorylation of NS5A, which seems to be required for viral production.

Does ledipasvir and sofosbuvir work?

Generic Name: ledipasvir-sofosbuvir It may sometimes be used with another antiviral medication (ribavirin). These drugs work by reducing the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover.

How much is Sofosbuvir cost?

Sofosbuvir (Sovaldi): This medication costs $1,000 per 400 mg pill. The total cost for a 12-week course is around $84,000, and doctors will typically prescribe it with other medicines, such as simeprevir.

Is pirfenidone a steroid?

An anti-inflammatory drug that is not a steroid.

Which common drug should be avoided when taking Ledipasvir and Sofosbuvir?

If you take ledipasvir and sofosbuvir and you also take a heart rhythm medicine called amiodarone: This combination of medicines can cause dangerous side effects on your heart.

What type of drug is sofosbuvir?

Sofosbuvir is in a class of antiviral medications called nucleotide polymerase inhibitors. It works by decreasing the amount of hepatitis C virus (HCV) in the body.