What is orofacial cleft?

Español (Spanish) Cleft lip and cleft palate are birth defects that occur when a baby’s lip or mouth do not form properly during pregnancy. Together, these birth defects commonly are called “orofacial clefts”.

Is orofacial cleft good or bad?

Orofacial cleft is one of the commonest congenital abnormalities which impacts negatively on the life of the individual and to a large extent affects the family. Caused by the interaction of environmental and genetic factors, this abnormality brings about decreased quality of life.

What are the different orofacial clefts?

Clinical and epidemiologic notes All orofacial clefts (cleft lip, cleft palate, and cleft lip with cleft palate) have similar non-genetic risk factors.

Is orofacial cleft a genetic disorder?

Orofacial clefts show strong familial aggregation, which suggests a major genetic component to their etiology. Marazita and Leslie 17 have recently reviewed the extensive history of genetic studies of orofacial clefts, which dates back to the 18 th century (see their Table 1).

When does cleft lip appear?

Cleft lip and cleft palate happen very early in pregnancy. Your baby’s lips form between 4 and 7 weeks of pregnancy, and the palate forms between 6 and 9 weeks of pregnancy. Oral clefts don’t have to happen together—a baby can have one without the other.

Can cleft lip heal?

Children with a cleft lip or palate will need several treatments and assessments as they grow up. A cleft is usually treated with surgery. Other treatments, such as speech therapy and dental care, may also be needed. Your child will be cared for by a specialist cleft team at an NHS cleft centre.

How many children a year are born with a cleft palate?

Cleft lip and cleft palate are common birth defects. About 1 or 2 in 1,000 babies (less than 1 percent) are born with cleft lip and palate each year in the United States.

Does cleft palate affect the brain?

Cognitive deficits in syndromic clefting are frequent and often severe (mental retardation). The cognitive deficits associated with isolated clefts of the lip and/or palate (ICLP) are less severe, but the functional consequences of these deficits should not be underestimated.

What is a hair lip called?

A cleft lip is an opening or split in the upper lip that occurs when developing facial structures in an unborn baby don’t close completely. Cleft lip may be unilateral or bilateral.

What is orofacial cleft and how is it treated?

What is an OFC cleft?

Orofacial clefts (OFCs) are common congenital malformations of the lip, palate, or both caused by complex genetic and environmental factors [1]. OFC may involve the lip, the roof of the mouth (hard palate), or the soft tissue in the back of the mouth (soft palate).

What is a cleft palate?

Cleft lip is a condition characterized by an opening in the upper lip, that may even extend to the nose. This opening may be unilateral (on one side) or bilateral (on both sides). It may also be found in the middle in many cases. A cleft palate is a condition in which there is an opening on the roof of the mouth that extends into the nose.

What are the different types of cleft disorders?

Stickler’s syndrome: It can cause cleft lip, cleft palate, myopia and joint pain. Loeys – Dietz syndrome: Can cause bifid uvula, aortic aneurysm, and hypertelorism. Hardikar syndrome: Cleft lip and palate, Hydronephrosis and intestinal obstruction. What are the different types of orofacial clefts?