What is Qtrap used for?
What is Qtrap used for?
QTRAP technology has the tools for your search, enabling you to screen for unknowns better than you can with triple quad technology. With the enhanced mass spec (EMS),enhanced resolution (ER) and enhanced product ion (EPI) scanning capabilities, QTRAP can help you find and characterize components in your sample.
What is Qtrap mass spectrometer?
The quadropule ion trap (Q-Trap) is a particular type of triple quadrupole mass spectrometer. The Q-Trap adds the ability to conduct (precursor to product to secondary product ion scanning (or MS3) thus providing additional selectivity. …
What is enhanced product ion scan?
The Enhanced Product Ion Scan is the standard method for performing MS/MS on the QTRAP instrument. It is actually a hybrid QqQ/LIT scan because it combines the capabilities of the QqQ with the LIT to achieve a performance level not possible with either analyzer alone.
How does triple quadrupole mass spectrometer work?
A triple-quadrupole mass spectrometer, also known as QqQ, is a tandem MS method in which the first and third quadrupoles act as mass filters and the second causes fragmentation of the analyte through interaction with a collision gas—it is a radiofrequency-only quadrupole, and can be used in either SIM or scan mode.
How does a linear ion trap work?
How it works. The LIT uses a set of quadrupole rods to confine ions radially and a static electrical potential on the end electrodes to confine the ions axially. The LIT can be used as a mass filter or as a trap by creating a potential well for the ions along the axis of the trap.
What is SIM scan?
Selected ion monitoring (SIM) is a technique widely used for trace analysis. In this technique, rather than the mass spectrometer being set to scan over a pre-defined mass range and record full mass spectra it is set to monitor the intensity of specific m/z values.
Who invented triple quadrupole mass spectrometer?
Christie G. Enke
Triple-quad mass spectrometry technology was invented by Christie G. Enke and Richard A. Yost in the late 1970’s. For a basic triple-quad instrument, two linear quadrupole analyzers are connected by a third quadrupole, where collision gas is introduced to fragment the ions.
What is the difference between single quadrupole and triple quadrupole?
Single quadrupole systems contain only one mass filtering quadrupole while triple quadrupole systems consist of three quadrupoles. During a mass scan, DC and RF voltages are ramped resulting in the acquisition of full scan mass spectra. Such spectra are typically used for qualitative data analysis.
Is ion trap mass analyzer?
Ion trap mass analyzers use a combination of electric or magnetic fields to capture or “trap” ions inside the mass analyzer. Last, ion cyclotron resonance (ICR) traps use a strong magnetic field to induce a radial orbit of ions, where the frequency of orbit in the magnetic field is a function m/z for the ion.
What is linear trap quadrupole?
The linear ion trap uses a set of quadrupole rods to confine ions radially and a static electrical potential on-end electrodes to confine the ions axially. The linear form of the trap can be used as a selective mass filter, or as an actual trap by creating a potential well for the ions along the axis of the electrodes.