What is the GSTM1 gene?

GSTM1 is a glutathione S-transferase (GST) which play a role in the detoxification of metabolites of environmental carcinogens including tobacco smoke. There is some evidence to suggest that people with common polymorphisms of these genes may have an increased susceptibility to a range of different cancers.

What does the GSTT1 gene do?

The protein encoded by this gene, glutathione S-transferase (GST) theta 1 (GSTT1), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds.

How can I increase my glutathione S-transferase?

Eating sulfur rich foods may increase glutathione levels in the body. Sulfur occurs in several amino acids, two of which — methionine and cysteine — are precursors for glutathione and therefore contribute to its synthesis .

Does green tea contain glutathione?

Glutathione is the main, and possibly most important, antioxidant directly produced by the body. Green tea consumption has been shown to significantly increase blood levels of glutathione, thereby raising systemic antioxidant capacity. …

Does asparagus have glutathione?

It’s also especially rich in glutathione, a detoxifying compound that can help destroy carcinogens. For this reason, asparagus may help fight or protect against certain cancers, including bone, breast, lung and colon cancers.

Does glutathione deplete zinc?

Glutathione is the major redox buffering agent in the cell and therefore important for mitigation of the adverse effects of oxidative stress. In mammalian cells, zinc deficiency is accompanied by a glutathione depletion.

Which is better collagen or glutathione?

While collagen deals primarily with the aesthetics of skin aging, glutathione is an antioxidant that helps combat free radicals, which can damage your body’s cells and affect many bodily processes.

Is caffeine bad for glutathione?

Conclusions: A coffee intake regimen, representing the average consumption of coffee drinkers in Italy, increased the plasma concentration of glutathione, but no significant increase in the plasma homocysteine concentration was detected.

Does cabbage have glutathione?

Those have a lot of the building blocks.” Broccoli, cauliflower, cabbage, and Brussels sprouts are examples of cruciferous vegetables. Other foods that are high in glutathione or its precursors include asparagus, potatoes, peppers, carrots, avocados, squash, spinach, and melons.

Why glutathione is not FDA approved?

The FDA has not approved any injectable products for skin lightening. Side effects on the use of injectable glutathione for skin lightening include toxic effects on the liver, kidneys, and nervous system. Also of concern is the possibility of Stevens Johnson Syndrome.

What is the length of the GSTM1 gene?

The GSTM1 gene is approximately 20 kb in length and is closely flanked by other mu class gene sequences.

What does GSTM1 stand for?

Glutathione S-transferase Mu 1 (gene name GSTM1) is a human glutathione S -transferase . Cytosolic and membrane -bound forms of glutathione S -transferase are encoded by two distinct supergene families.

Are GSTT1 and GSTM1 genotypes found in the tumor area?

RESULTS: in one patient, we detected null GSTT1 and GSTM1 genotypes in the tumor area, in contrast to the presence of both genes in the proximal and distal margins. We found EBV-DNA and H. pylori in the tumor area and also in the proximal and distal margins.

Is there a relationship between GSTM1 and cancer?

Latest Publications: GSTM1 (cancer-related) When considered together, GSTM1 and GSTT1 genotypes were found to be associated with an increased risk of breast cancer. The relationship between GSTM1 and GSTT1 gene deletions and breast cancer risk was substantially altered by consumption of Smoked Meat/Vegetable.